Publications

2018

Schwarz, M., Schall, K., Kallis, E., Eustermann, S., Guariento, M., Moldt, M., Hopfner, K.P., and Michaelis, J. (2018). Single-molecule nucleosome remodeling by INO80 and effects of histone tails. FEBS letters.

View publication

Lavagi, I., Krebs, S., Simmet, K., Beck, A., Zakhartchenko, V., Wolf, E., and Blum, H. (2018). Single-cell RNA sequencing reveals developmental heterogeneity of blastomeres during major genome activation in bovine embryos. Sci Rep 8, 4071.

View publication

Mura, F., Gradziuk, G., and Broedersz, C.P. (2018). Non-equilibrium scaling behaviour in driven soft biological assemblies. arXiv preprint arXiv:180302797.

View publication

Franquelim, H.G., Khmelinskaia, A., Sobczak, J.P., Dietz, H., and Schwille, P. (2018). Membrane sculpting by curved DNA origami scaffolds. Nat Commun 9, 811.

View publication

Tian, P., Steward, A., Kudva, R., Su, T., Shilling, P.J., Nickson, A.A., Hollins, J.J., Beckmann, R., Von Heijne, G., Best, R., et al. (2018). The Folding Pathway of an Ig Domain is Conserved On and Off the Ribosome. bioRxiv.

View publication

Stapor, P., Froehlich, F., and Hasenauer, J. (2018). Optimization and uncertainty analysis of ODE models using second order adjoint sensitivity analysis. bioRxiv.

View publication

Bojer, M., Graf, I.R., and Frey, E. (2018). Self-organized system size oscillation of a stochastic lattice-gas model. arXiv preprint arXiv:180303942.

View publication

Bergeler, S., and Frey, E. (2018). Regulation of Pom cluster dynamics in Myxococcus xanthus. arXiv preprint arXiv:180106133.

View publication

Denk, J., Kretschmer, S., Halatek, J., Hartl, C., Schwille, P., and Frey, E. (2018). MinE conformational switching confers robustness on self-organized Min protein patterns. Proceedings of the National Academy of Sciences of the United States of America. DOI: 10.1073/pnas.1719801115

View publication

Reiser, A., Zorn, M.L., Murschhauser, A., and Rädler, J.O. (2018). Single Cell Microarrays Fabricated by Microscale Plasma-Initiated Protein Patterning (μPIPP). In Cell-Based Microarrays (Springer), pp. 41-54.

View publication

Dietrich, M., Le Roy, H., Brückner, D.B., Engelke, H., Zantl, R., Rädler, J.O., and Broedersz, C.P. (2018). Guiding 3D cell migration in deformed synthetic hydrogel microstructures. Soft matter 14, 2816 -2826.

View publication

Villaverde, A.F., Froehlich, F., Weindl, D., Hasenauer, J., and Banga, J.R. (2018). Benchmarking optimization methods for parameter estimation in large kinetic models. bioRxiv.

View publication

Eustermann, S., Schall, K., Kostrewa, D., Lakomek, K., Strauss, M., Moldt, M., and Hopfner, K.P. (2018). Structural basis for ATP-dependent chromatin remodelling by the INO80 complex. Nature.

View publication

Froehlich, F., Reiser, A., Fink, L., Woschee, D., Ligon, T., Theis, F., Raedler, J., and Hasenauer, J. (2018). Multi-Experiment Nonlinear Mixed Effect Modeling of Single-Cell Translation Kinetics after Transfection. bioRxiv.

View publication

Kretschmer, S., Harrington, L., and Schwille, P. (2018). Reverse and forward engineering of protein pattern formation. Philosophical Transactions of the Royal Society B: Biological Sciences 373.

View publication

von Bronk, B., Götz, A. and Opitz, M., (2018), Complex microbial systems across different levels of description, Physical Biology, 15, 5

View publication

2017

Chlis, N.K., Alexander Wolf, F., and Theis, F.J. (2017). Model-based branching point detection in single-cell data by K-Branches clustering. Bioinformatics.

View publication

Vogel, S.K., Greiss, F., Khmelinskaia, A., and Schwille, P. (2017). Control of lipid domain organization by a biomimetic contractile actomyosin cortex. eLife 6.

View publication

Agerschou, E.D., Mast, C.B., Braun, D. (2017). Emergence of life from trapped nucleotides? Non-equilibrium behavior of oligonucleotides in thermal gradients. Synlett 28, 56-63.

View publication

Fröhlich, F., Kaltenbacher, B, Theis, F.J., Hasenauer, J. (2017). Scalable parameter estimation for genome-scale biochemical reaction networks. Plos Comput Biol 13(1): e1005331.

View publication

Gerland, T.A., Sun, B., Smialowski, P., Lukacs, A., Thomae, A.W., and Imhof, A. (2017). The Drosophila speciation factor HMR localizes to genomic insulator sites. PloS one 12, e0171798.

View publication

Greiss, F., Kriegel, F., Braun, D. (2017). Probing the cooperativity of binding networks with high-throughput thermophoresis. Analytical Chemistry 89 (4), 2592-2597.

View publication

Hinzpeter, F., Gerland, U., Tostevin, F. (2017). Optimal compartmentalization strategies for metabolic microcompartments. Biophys J 112, 767 – 779

View publication

Michel, M., Demel, C., Zacher, B., Schwalb, B., Krebs, S., Blum, H., Gagneur, J., and Cramer, P. (2017). TT-seq captures enhancer landscapes immediately after T-cell stimulation. Mol Syst Biol 13, 920.

View publication

Ponce, L.P., Fenn, N.C., Moritz, N., Krupka, C., Kozik, J.H., Lauber, K., Subklewe, M., and Hopfner, K.P. (2017). SIRPalpha-antibody fusion proteins stimulate phagocytosis and promote elimination of acute myeloid leukemia cells. Oncotarget 8, 11284-11301.

View publication

Collado, J., and Fernandez-Busnadiego, R. (2017). Deciphering the molecular architecture of membrane contact sites by cryo-electron tomography. Biochimica et biophysica acta.

View publication

Schauer, T., Ghavi-Helm, Y., Sexton, T., Albig, C., Regnard, C., Cavalli, G., Furlong, E.E.M., and Becker, P.B. (2017). The Drosophila Dosage Compensation Complex activates target genes by chromosome looping within the active compartment. bioRxiv.

View publication

Barthels, C., Ogrinc, A., Steyer, V., Meier, S., Simon, F., Wimmer, M., Blutke, A., Straub, T., Zimber-Strobl, U., Lutgens, E., et al. (2017). CD40-signalling abrogates induction of RORγt(+) Treg cells by intestinal CD103(+) DCs and causes fatal colitis. Nature Communications 8, 14715.

View publication

Schueder, F., Strauss, M.T., Hoerl, D., Schnitzbauer, J., Schlichthaerle, T., Strauss, S., Yin, P., Harz, H., Leonhardt, H., and Jungmann, R. (2017). Universelles Superauflösungs-Multiplexing durch DNA-Austausch. Angewandte Chemie 129, 4111-4114.

View publication

von Bronk, B., Schaffer, S.A., Gotz, A., and Opitz, M. (2017). Effects of stochasticity and division of labor in toxin production on two-strain bacterial competition in Escherichia coli. PLoS biology 15, e2001457.

View publication

Schnitzbauer, J., Strauss, M.T., Schlichthaerle, T., Schueder, F., and Jungmann, R. (2017). Super-resolution microscopy with DNA-PAINT. Nature protocols 12, 1198-1228.

View publication

Shetty, A., Kallgren, S.P., Demel, C., Maier, K.C., Spatt, D., Alver, B.H., Cramer, P., Park, P.J., and Winston, F. (2017). Spt5 Plays Vital Roles in the Control of Sense and Antisense Transcription Elongation. Molecular cell 66, 77-88 e75.

View publication

Su, T., Cheng, J., Sohmen, D., Hedman, R., Berninghausen, O., von Heijne, G., Wilson, D.N., and Beckmann, R. (2017). The force-sensing peptide VemP employs extreme compaction and secondary structure formation to induce ribosomal stalling. eLife 6.

View publication

Krzyszton, R., Salem, B., Lee, D.J., Schwake, G., Wagner, E., Rädler, J.O. (2017). Microfluidic self-assembly of folate-targeted monomolecular siRNA-lipid nanoparticles. Nanoscale 9, 7442-7453.

View publication

Kesel, S., von Bronk, B., Falcon Garcia, C., Gotz, A., Lieleg, O., and Opitz, M. (2017). Matrix composition determines the dimensions of Bacillus subtilis NCIB 3610 biofilm colonies grown on LB agar. RSC Advances 7, 31886-31898.

View publication

Leonaite, B., Han, Z., Basquin, J., Bonneau, F., Libri, D., Porrua, O., and Conti, E. (2017). Sen1 has unique structural features grafted on the architecture of the Upf1-like helicase family. The EMBO journal 36, 1590-1604.

View publication

Bäuerlein, F.J.B., Saha, I., Mishra, A., Kalemanov, M., Martínez-Sánchez, A., Klein, R., Dudanova, I., Hipp, M.S., Hartl, F.U., Baumeister, W., Fernández-Busnadiego, R. (2017). In Situ Architecture and Cellular Interactions of PolyQ Inclusions. Cell 171, 179-187 e110.

View publication

Avsec, Z., Barekatain, M., Cheng, J., Gagneur, J. (2017). Modeling positional effects of regulatory sequences with spline transformations increases prediction accuracy of deep neural networks. Bioinformatics doi.10.1093/bioinformatics/btx727

View publication

Milger, K., Gotschke, J., Krause, L., Nathan, P., Alessandrini, F., Tufman, A., Fischer, R., Bartel, S., Theis, F.J., Behr, J., et al. (2017). Identification of a plasma miRNA biomarker signature for allergic asthma: A translational approach. Allergy 72, 1962-1971.

View publication

Cheng, J., Maier, K.C., Avsec, Z., Rus, P., and Gagneur, J. (2017). Cis-regulatory elements explain most of the mRNA stability variation across genes in yeast. Rna 23, 1648-1659.

View publication

Kremer, L.S., Bader, D.M., Mertes, C., Kopajtich, R., Pichler, G., Iuso, A., Haack, T.B., Graf, E., Schwarzmayr, T., Terrile, C., et al. (2017). Genetic diagnosis of Mendelian disorders via RNA sequencing. Nat Commun 8, 15824.

View publication

Solis-Mezarino, V., and Herzog, F. (2017). compleXView: a server for the interpretation of protein abundance and connectivity information to identify protein complexes. Nucleic acids research.

View publication

Gnesotto, F., Mura, F., Gladrow, J., and Broedersz, C.P. (2017). Broken detailed balance and non-equilibrium dynamics in living systems. In ArXiv e-prints.

View publication

Ammar, C., Berchtold, E., Csaba, G., Schmidt, A., Imhof, A., and Zimmer, R. (2017). Multi-reference spectral library yields almost complete coverage of heterogeneous LC-MS/MS data sets. bioRxiv, 180448.

View publication

Buttner, M., Miao, Z., Wolf, A., Teichmann, S.A., and Theis, F.J. (2017). Assessment of batch-correction methods for scRNA-seq data with a new test metric. bioRxiv, 200345.

View publication

Kater, L., Thoms, M., Barrio-Garcia, C., Cheng, J., Ismail, S., Ahmed, Y.L., Bange, G., Kressler, D., Berninghausen, O., Sinning, I., et al. (2017). Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes. Cell 171, 1599-1610. e1514.

View publication

Tritschler, S., Theis, F.J., Lickert, H., and Böttcher, A. (2017). Systematic single-cell analysis provides new insights into heterogeneity and plasticity of the pancreas. Molecular metabolism 6, 974-990.

View publication

Loos, C., Moeller, K., Fröhlich, F., Hucho, T., and Hasenauer, J. (2017). Mechanistic hierarchical population model identifies latent causes of cell-to-cell variability. bioRxiv, 171561.

View publication

Kretschmer, S., Zieske, K., and Schwille, P. (2017). Large-scale modulation of reconstituted Min protein patterns and gradients by defined mutations in MinE’s membrane targeting sequence. PloS one 12, e0179582.

View publication

Froehlich, F., Kessler, T., Weindl, D., Shadrin, A., Schmiester, L., Hache, H., Muradyan, A., Schuette, M., Lim, J.-H., Heinig, M., et al. (2017). Efficient parameterization of large-scale mechanistic models enables drug response prediction for cancer cell lines. bioRxiv, 174094.

View publication

Stricker, G., Engelhardt, A., Schulz, D., Schmid, M., Tresch, A., and Gagneur, J. (2017). GenoGAM: genome-wide generalized additive models for ChIP-Seq analysis. Bioinformatics, btx150.

View publication

Fischer, D.S., Fiedler, A.K., Kernfeld, E., Genga, R.M., Hasenauer, J., Maehr, R., and Theis, F.J. (2017). Beyond pseudotime: Following T-cell maturation in single-cell RNAseq time series. bioRxiv, 219188.

View publication

Angerer, P., Simon, L., Tritschler, S., Wolf, F.A., Fischer, D., and Theis, F.J. (2017). Single cells make big data: New challenges and opportunities in transcriptomics. Current Opinion in Systems Biology 4, 85-91.

View publication

Schauer, T., Ghavi‐Helm, Y., Sexton, T., Albig, C., Regnard, C., Cavalli, G., Furlong, E.E., and Becker, P.B. (2017). Chromosome topology guides the Drosophila Dosage Compensation Complex for target gene activation. EMBO reports 18, 1854-1868.

View publication

Biselli, E., Agliari, E., Barra, A., Bertani, F.R., Gerardino, A., De Ninno, A., Mencattini, A., Di Giuseppe, D., Mattei, F., Schiavoni, G., et al. (2017). Organs on chip approach: a tool to evaluate cancer-immune cells interactions. Sci Rep-Uk 7, 12737.

View publication

Graf, I.R., and Frey, E. (2017). Generic transport mechanisms for molecular traffic in cellular protrusions. Phys Rev Lett 118, 128101.

View publication

Auer, A., Strauss, M.T., Schlichthaerle, T., and Jungmann, R. (2017). Fast, background-free DNA-PAINT imaging using FRET-based probes. Nano letters 17, 6428-6434.

View publication

Miyagi, A., Ramm, B., Schwille, P., and Scheuring, S. (2017). High-speed AFM reveals the inner workings of the MinDE protein oscillator. Nano letters.

View publication

Stapor, P., Weindl, D., Ballnus, B., Hug, S., Loos, C., Fiedler, A., Krause, S., Hroß, S., Fröhlich, F., and Hasenauer, J. (2017). PESTO: Parameter EStimation TOolbox. Bioinformatics.

View publication

Yepez M, V.A., Kremer, L.S., Iuso, A., Gusic, M., Kopajtich, R., Konarikova, E., Nadel, A., Wachutka, L., Prokisch, H., and Gagneur, J. (2017). OCR-Stats: Robust estimation and statistical testing of mitochondrial respiration activities using Seahorse XF Analyzer. bioRxiv, 231522.

View publication

Bauer, M., Graf, I.R., Ngampruetikorn, V., Stephens, G.J., and Frey, E. (2017). Exploiting ecology in drug pulse sequences in favour of population reduction. Plos Comput Biol 13, e1005747.

View publication

Ligon, T.S., Fröhlich, F., Chi, O.T., Banga, J.R., Balsa-Canto, E., and Hasenauer, J. (2017). GenSSI 2.0: Multi-experiment structural identifiability analysis of SBML models. Bioinformatics.

View publication

Garzorz-Stark, N., Lauffer, F., Krause, L., Thomas, J., Atenhan, A., Franz, R., Roenneberg, S., Boehner, A., Jargosch, M., Batra, R., et al. (2017). Toll-like receptor 7/8 agonists stimulate plasmacytoid dendritic cells to initiate TH17-deviated acute contact dermatitis in human subjects. Journal of Allergy and Clinical Immunology.

View publication

Schumacher, D., Bergeler, S., Harms, A., Vonck, J., Huneke-Vogt, S., Frey, E., and Søgaard-Andersen, L. (2017). The PomXYZ Proteins Self-Organize on the Bacterial Nucleoid to Stimulate Cell Division. Developmental Cell 41, 299-314. e213.

View publication

Fröhlich, F., Loos, C., and Hasenauer, J. (2017). Scalable Inference of Ordinary Differential Equation Models of Biochemical Processes. arXiv preprint arXiv:171108079.

View publication

Ait-El-Mkadem, S., Dayem-Quere, M., Gusic, M., Chaussenot, A., Bannwarth, S., François, B., Genin, E.C., Fragaki, K., Volker-Touw, C.L.M., Vasnier, C., et al. Mutations in MDH2, Encoding a Krebs Cycle Enzyme, Cause Early-Onset Severe Encephalopathy. The American Journal of Human Genetics 100, 151-159.

View publication

Blutke, A., Renner, S., Flenkenthaler, F., Backman, M., Haesner, S., Kemter, E., Landstrom, E., Braun-Reichhart, C., Albl, B., Streckel, E., et al. (2017). The Munich MIDY Pig Biobank – A unique resource for studying organ crosstalk in diabetes. Mol Metab 6, 931-940.

View publication

2016

Denk, J., Huber, L., Reithmann, E., and Frey, E. (2016). Active Curved Polymers Form Vortex Patterns on Membranes. Phys Rev Lett 116.

View publication

Dau, T., Edeleva, E.V., Seidel, S.A.I., Stockley, R.A., Braun, D., and Jenne, D.E. (2016). Quantitative analysis of protease recognition by inhibitors in plasma using microscale thermophoresis. Sci Rep-Uk 6, 35413.

View publication

Chatzopoulou, E.I., Roskopf, C.C., Sekhavati, F., Braciak, T.A., Fenn, N.C., Hopfner, K.-P., Oduncu, F.S., Fey, G.H., and Rädler, J.O. (2016). Chip-based platform for dynamic analysis of NK cell cytolysis mediated by a triplebody. Analyst 141, 2284-2295.

View publication

Eser, P., Wachutka, L., Maier, K.C., Demel, C., Boroni, M., Iyer, S., Cramer, P., and Gagneur, J. (2016). Determinants of RNA metabolism in the Schizosaccharomyces pombe genome. Mol Syst Biol 12, 857.

View publication

Fröhlich, F., Theis, F.J., Rädler, J.O., and Hasenauer, J. (2016). Parameter estimation for dynamical systems with discrete events and logical operations. Bioinformatics.

View publication

Fröhlich, F., Thomas, P., Kazeroonian, A., Theis, F.J., Grima, R., and Hasenauer, J. (2016). Inference for Stochastic Chemical Kinetics Using Moment Equations and System Size Expansion. Plos Comput Biol 12.

View publication

Greiss, F., Deligiannaki, M., Jung, C., Gaul, U., and Braun, D. (2016). Single-Molecule Imaging in Living Drosophila Embryos with Reflected Light-Sheet Microscopy. Biophys J 110, 939-946.

View publication

Haghverdi, L., Büttner, M., Wolf, F.A., Buettner, F., and Theis, F.J. (2016). Diffusion pseudotime robustly reconstructs lineage branching. Nature methods 13, 845-848.

View publication

Kazeroonian, A., Fröhlich, F., Raue, A., Theis, F.J., and Hasenauer, J. (2016). CERENA: ChEmical REaction Network Analyzer-A Toolbox for the Simulation and Analysis of Stochastic Chemical Kinetics. PloS one 11, e0146732.

View publication

Khmelinskaia, A., Franquelim, H.G., Petrov, E.P., and Schwille, P. (2016). Effect of anchor positioning on binding and diffusion of elongated 3D DNA nanostructures on lipid membranes. J Phys D Appl Phys 49.

View publication

Kretschmer, S., and Schwille, P. (2016). Pattern formation on membranes and its role in bacterial cell division. Current opinion in cell biology 38, 52-59.

View publication

Mura, F., Zaccone., A. (2016). Effects of shear flow on phase nucleation and crystallization. Physical Review E 93, 042803.

View publication

Ramirez, D., Garcia-Soriano, D.A., Raso, A., Feingold, M., Rivas, G., and Schwille, P. (2016). Chiral vortex dynamics on membranes is an intrinsic property of FtsZ, driven by GTP hydrolysis. bioRxiv.

View publication

Schmidt, C., Becker, T., Heuer, A., Braunger, K., Shanmuganathan, V., Pech, M., Berninghausen, O., Wilson, D.N., and Beckmann, R. (2016). Structure of the hypusinylated eukaryotic translation factor eIF-5A bound to the ribosome. Nucleic acids research 44, 1944-1951.

View publication

Schmidt, C., Kowalinski, E., Shanmuganathan, V., Defenouillere, Q., Braunger, K., Heuer, A., Pech, M., Namane, A., Berninghausen, O., Fromont-Racine, M., Jacquier, A., Conti, E., Becker, T., Beckmann, R. (2016). The cryo-EM structure of a ribosome-Ski2-Ski3-Ski8 helicase complex. Science 354, 1431-1433.

View publication

Schwalb, B., Michel, M., Zacher, B., Fruhauf, K., Demel, C., Tresch, A., Gagneur, J., and Cramer, P. (2016). TT-seq maps the human transient transcriptome. Science 352, 1225-1228.

View publication

Eraslan, G., Arloth, J., Martins, J., Iurato, S., Czamara, D., Binder, E.B., Theis, F.J., and Mueller, N.S. (2016). DeepWAS: Directly integrating regulatory information into GWAS using deep learning supports master regulator MEF2C as risk factor for major depressive disorder. bioRxiv.

View publication

Schlichthaerle, T., Strauss, M.T., Schueder, F., Woehrstein, J.B., and Jungmann, R. (2016). DNA nanotechnology and fluorescence applications. Current opinion in biotechnology 39, 41-47.

View publication

Schiller, C.B., Braciak, T.A., Fenn, N.C., Seidel, U.J., Roskopf, C.C., Wildenhain, S., Honegger, A., Schubert, I.A., Schele, A., Lämmermann, K., et al. (2016). CD19-specific triplebody SPM-1 engages NK and γδ T cells for rapid and efficient lysis of malignant B-lymphoid cells. Oncotarget 7, 83392.

View publication

Roskopf, C.C., Braciak, T.A., Fenn, N.C., Kobold, S., Fey, G.H., Hopfner, K.-P., and Oduncu, F.S. (2016). Dual-targeting triplebody 33-3-19 mediates selective lysis of biphenotypic CD19+ CD33+ leukemia cells. Oncotarget 7, 22579.

View publication

2015

Angerer, P., Haghverdi, L., Büttner, M., Theis, F.J., Marr, C., and Buettner, F. (2015). destiny: diffusion maps for large-scale single-cell data in R. Bioinformatics.

View publication

Bader, D.M., Wilkening, S., Lin, G., Tekkedil, M.M., Dietrich, K., Steinmetz, L.M., and Gagneur, J. (2015). Negative feedback buffers effects of regulatory variants. Molecular systems biology 11, 785.

View publication

Haack, T.B., Staufner, C., Kopke, M.G., Straub, B.K., Kolker, S., Thiel, C., Freisinger, P., Baric, I., McKiernan, P.J., Dikow, N., Harting, I., Beisse, F., Burgard, P., Kotzaeridou, U., Kühr, J., Himbert, U., Taylor, R.W., Distelmaier, F., Vockley, J., Ghaloul-Gonzalez, L., Zschocke, J., Kremer, L.S., Graf, E., Schwarzmayr, T., Bader, D.M., Gagneur, J., et al. (2015). Biallelic Mutations in NBAS Cause Recurrent Acute Liver Failure with Onset in Infancy. American journal of human genetics 97, 163-169.

View publication

Reichl, M., Herzog, M., Greiss, F., Wolff, M., and Braun, D. (2015). Understanding the similarity in thermophoresis between single- and double-stranded DNA or RNA. Physical review E, Statistical, nonlinear, and soft matter physics 91, 062709.

View publication

Kretschmer, S., and Schwille, P. (2015). Rekonstitution biologischer Selbstorganisation in vitro. BIOspektrum 21, 148-150.

View publication

Arloth, J., Bader, D.M., Röh, S., and Altmann, A. (2015). Re-Annotator: Annotation Pipeline for Microarray Probe Sequences. PloS one 10, e0139516.

View publication

Beckert, B., Kedrov, A., Sohmen, D., Kempf, G., Wild, K., Sinning, I., Stahlberg, H., Wilson, D.N., and Beckmann, R. (2015). Translational arrest by a prokaryotic signal recognition particle is mediated by RNA interactions. Nature structural & molecular biology 22, 767-773.

View publication

Matheisl, S., Berninghausen, O., Becker, T., and Beckmann, R. (2015). Structure of a human translation termination complex. Nucleic acids research 43, 8615-8626.

View publication

Sekhavati, F., Endele, M., Rappl, S., Marel, A.-K., Schroeder, T., and Rädler, J.O. (2015). Marker-free detection of progenitor cell differentiation by analysis of Brownian motion in micro-wells. Integrative Biology 7, 178-183.

View publication

2014

Fröhlich, F., Hross, S., Theis, F.J., and Hasenauer, J. (2014). Radial Basis Function Approximations of Bayesian Parameter Posterior Densities for Uncertainty Analysis. In: Mendes P., Dada J.O., Smallbone K. (eds) Computational Methods in Systems Biology. CMSB 2014. Lecture Notes in Computer Science, vol 8859. Springer, Cham

View publication

Fröhlich, F., Theis, F.J., and Hasenauer, J. (2014).  Uncertainty Analysis for Non-identifiable Dynamical Systems: Profile Likelihoods, Bootstrapping and More. In: Mendes P., Dada J.O., Smallbone K. (eds) Computational Methods in Systems Biology. CMSB 2014. Lecture Notes in Computer Science, vol 8859. Springer, Cham

View publication

Graf, A., Krebs, S., Heininen-Brown, M., Zakhartchenko, V., Blum, H., and Wolf, E. (2014). Genome activation in bovine embryos: review of the literature and new insights from RNA sequencing experiments. Animal reproduction science 149, 46-58.

View publication

Kretschmer, S., and Schwille, P. (2014). Toward Spatially Regulated Division of Protocells: Insights into the E. coli Min System from in Vitro Studies. Life 4, 915-928.

View publication

Hopfner, K.P. (2014). RIG-I holds the CARDs in a game of self versus nonself. Molecular cell 55, 505-507.

View publication

Hopfner, K.P. (2014). ATP puts the brake on DNA double‐strand break repair. Bioessays 36, 1170-1178.

View publication

2013

Schulz, D., Schwalb, B., Kiesel, A., Baejen, C., Torkler, P., Gagneur, J., Soeding, J., and Cramer, P. (2013). Transcriptome surveillance by selective termination of noncoding RNA synthesis. Cell 155, 1075-1087.

View publication